“Noopept” or “Nootropil” – which is better? Comparison of drugs

In addition to organic and functional disorders due to diseases, injuries and unhealthy lifestyles, there are many natural factors that negatively affect brain function. Stress, poor sleep, genetics and aging also create a need for drugs that help the brain cope with impaired metabolic capabilities. Among the many nootropic drugs, two similar drugs Piracetam and Picamilon have been available on the domestic pharmacological market for many years. Let's take a closer look at their similarities and differences.

pharmachologic effect

Manufacturer: JSC AKRIKHIN (Russia)
Release form: tablets, injection solution

Active ingredient: nicotinoyl gamma-aminobutyric acid

Analogs: Cortexin, Cytoflavin, Nootropil

Picamilon is a nootropic that normalizes blood circulation in the brain and eliminates cerebral insufficiency. The medication reduces vascular resistance, stimulates the rate of cerebral blood flow, and has a diluting, vasodilating effect.

The drug normalizes tissue metabolism, improves cognitive disorders (memory, concentration), eliminates stress, fear, and increases physical endurance.

Noopept or Nootropil

In healthy people, the effect of using nootropics is weak or absent altogether. Medicines are beneficial for chronic fatigue, in children with developmental defects, and for the elderly. Medicines are successfully used in cardiology: for angina pectoris, post-infarction conditions, and coronary artery disease.

You can improve thought processes in different ways - speed up the movement of impulses between brain neurons due to increased intracranial blood flow. A group of nootropics has these advantages. But it is worth understanding that each of them has its own specifics. Nootropil and Noopept – what’s the difference, let’s try to figure it out in more detail.

These drugs have their own special characteristics. Medicines in this group of nootropics do not have one mechanism of action. It is assumed that positive effects are achieved through:

• direct stimulation of transcallosal potentials;
• influence on neurons;
• improving blood flow in the brain;
• antihypoxic, antiedematous and antiplatelet effects.

Nowadays, the main mechanism of action of such drugs is considered to be the effect on bioenergetic and metabolic processes in the nerve cell. A similar effect is achieved through interaction with the neurotransmitter systems of the brain.

Manufacturers of this class of stimulants claim that their medications are characterized by rapid penetration through the BBB, increasing the rate and utilization of sugars in the cerebral cortex, hypothalamus, subcortical ganglia and cerebellum, improving the metabolic processes of nucleic acids, activating the synthesis of protein, ATP and RNA.

These medications differ in composition. The active component of Noopept is cycloprolylglycine. This substance is an analogue of an endogenous neuropeptide, which is capable of binding to neuronal receptors, after which it enhances the effect of the specific mediator acetylcholine.

This anabolic for the brain provides a reduction in the toxic and stimulating effects of glutamate for the following diagnoses:

Noopept is also used for the following conditions:

• after simple traumatic brain injuries (post-concussion syndrome) with subjective symptoms;
• psychogenic pathologies (fatigue, apathy, headache);
• encephalopathy;
• vascular insufficiency of the brain;
• decrease in intellectual abilities.

The drug Noopept has a smaller list of side effects, with the exception of individual intolerance to the substance and, in rare cases, hypertension. A distinctive feature of this medication is the number of effective doses.

This figure is an order of magnitude lower than that of nootropil. This partly creates the relative safety of Noopept, which makes it possible to use it as a psychological tool for influencing a certain group of people with hypochondria.

Nootropil contains the active ingredient piracetam. It is a cyclic derivative of gamma-aminobutyric acid, a certain inhibitory mediator of the central nervous system. The advantages of the drug are:

• direct effect on the central nervous system;
• improvement of cognitive processes;
• the main component improves communication between both hemispheres of the brain;
• it activates mental activity, protects brain cells from hypoxia (oxygen starvation).

Nootropil has a positive effect on the central nervous system in the following way: it inhibits excitation, improves metabolism and microcirculation, systematically affecting the specific characteristics of the blood, and does not provoke a vasodilator effect.

Indications for use of Picamilon

The drug is prescribed for the following diseases and conditions:

• vegetative-vascular dystonia;
• cerebrovascular insufficiency due to a stroke or transient cerebrovascular accident;
• consequences of traumatic brain injury;
• infections of the central and peripheral nervous system of various origins;
• paroxysmal headaches (migraine);
• encephalopathy of various origins.

Picamilon effectively relieves feelings of fear, tension, irritability, and asthenic conditions accompanying various neuropsychiatric diseases. The medication improves the psychosomatic state in the treatment of chronic alcoholism.

Medicines for the brain

Nowadays, the pharmacy chain offers a huge number of medicines that help activate brain activity, improve concentration, restore memory and intellectual abilities.
In addition, such drugs make it possible to stop the aging process, restore microcirculation, and eliminate the formation of blood clots. The components included in the medicines, when used correctly, strengthen blood vessels and restore their elasticity and strength.

They also thin the blood, which protects the human body from complications such as stroke, heart attack and blood clots.

Modern cardiology cannot be imagined without drugs from the beta-blocker group, of which more than 30 names are currently known.

The need to include beta-blockers in the treatment program for cardiovascular diseases (CVD) is obvious: over the past 50 years of cardiac clinical practice, beta-blockers have taken a strong position in the prevention of complications and in the pharmacotherapy of arterial hypertension (AH), coronary heart disease (CHD), chronic heart failure (CHF), metabolic syndrome (MS), as well as some forms of tachyarrhythmias. Traditionally, in uncomplicated cases, drug treatment of hypertension begins with beta-blockers and diuretics, which reduce the risk of myocardial infarction (MI), cerebrovascular accident and sudden cardiogenic death.

In the 90s, it was established that beta-adrenergic receptors are divided into three subtypes:

• beta3-adrenergic receptors, localized primarily on adipocyte membranes, are involved in thermogenesis and lipolysis.
  Antiarrhythmic effect of beta-blockers

  , based on their ability to reduce the adrenergic effect on the heart, leads to:

• slowing down conduction in the AV junction and increasing the duration of the effective refractory period of the AV junction, lengthening the PQ interval (negative dromotropic effect).
  Beta-blockers increase the threshold for the occurrence of ventricular fibrillation in patients with acute MI and can be considered as a means of preventing fatal arrhythmias in the acute period of MI.

  Hypotensive effect

  beta blockers are due to:

• increased levels of prostaglandins in the blood.
  Drugs from the group of beta-blockers differ in the presence or absence of cardioselectivity, intrinsic sympathetic activity, membrane-stabilizing, vasodilating properties, solubility in lipids and water, effect on platelet aggregation, and also in duration of action.

  How to improve memory drugs

  Let's look at the drugs that you can buy at the pharmacy without a prescription:

  Bilobil (tanakan, memoplant, gingogink, bilobil forte, ginkgo biloba). Capsules 40 mg

  This is a herbal preparation of complex action - an extract from the leaves of the Ginkgo Biloba plant, containing substances that can act mainly on the vascular system of the brain, improve blood flow in the smallest vessels that supply blood to nerve cells. The drug has a mild antidepressant effect and increases the ability to remember.

  Recommended in old age, with age-related changes in cerebral circulation, manifested by dizziness, memory loss, sleep disturbances, anxiety, tinnitus, with the consequences of traumatic brain injuries, after a stroke. At a young age - with increased fatigue, decreased concentration.

  Read also:  Cortexin in the treatment of cerebral pathology

  Glycine 100 mg. Sublingual tablets. This is the safest drug, because is included in the metabolic processes of brain cells like a natural molecule of the body (amino acid glycine). It is easily excreted from the body, does not accumulate in tissues, and is not addictive.

  Glycine can be taken not only for illnesses, but also for healthy people in situations of increased mental and mental stress, emotional instability, prolonged stress, sleep disorders, and for students during exam periods.

  Reduces the toxic effect of alcohol.

  Aminalon (250 mg, tablets). Gamma-aminobutyric acid. Affects metabolic processes in brain cells, promotes the absorption of glucose - a source of energy for nerve cells. Improves memory, thinking, promotes restoration of impaired functions after a stroke.

  It is used in the prevention of motion sickness in transport, for alcoholic lesions of the nervous system, for residual effects after traumatic brain injuries, in the complex treatment of hypertension due to its mild hypotensive effect.

  General tonic drugs

  Eleutherococcus extract (tablets, liquid extract)

  Prescribed for overwork, after infectious diseases, restores physical and mental performance, increases the body's adaptive capabilities.

  Traditional medicine recipes to improve memory

  Infusion of clover flowers. Collect the heads from flowering plants, dry them, pour 2 tablespoons into a thermos. crushed flowers, add 2 cups of hot water and leave for 2 hours. Strain, take 1/3 cup 30 minutes before meals for 3 months.

  A decoction of rowan bark. 1 tbsp. l. dry crushed rowan bark, pour 250 ml of water and boil for 10 minutes. Leave for 6 hours, take 1 tbsp. l. 3 times a day for a month. Repeat the course 3 times a year.

  Young pine buds. In spring, eat 3-4 pine buds 2-3 times a day before meals.

  Medicines that can only be taken after consulting a doctor

  This group of drugs is available by prescription and is prescribed by a doctor only for any diseases, since the drugs are not harmless and have contraindications and side effects.

  Piracetam (Lucetam, Memotropil, Nootropil, Cerebril, Escotropil, Noocetam, Stamin).

  A classic representative of nootropic drugs, it is available in capsules for oral administration and ampoules with a solution for parenteral administration. The course of treatment ranges from 2-3 weeks to 3-6 months. Dosed individually depending on the indications. For chronic conditions, courses of treatment must be repeated.

  It has a psychostimulating effect in high doses. Contraindicated in severe kidney disease, pregnancy and breastfeeding, hemorrhagic stroke, chorea, depression with mental agitation, allergies to the drug.

  Encephabol (pyritinol). Available in tablets for oral administration and in the form of a suspension.

  It is widely used in pediatric practice from the 3rd day after birth for congenital brain pathologies , as well as for mental retardation.

  In adults – with disorders of cognitive functions of various origins. Duration of treatment is from 8 to 12 weeks. If necessary, as prescribed by the doctor, the courses are repeated.

  Phenotropil. Pills. A pronounced effect on memory functions, speed of thinking, concentration, as well as a general tonic and moderate psychostimulating effect with increased ability to work and resistance to stress.

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  Step-by-step course for mastering the skill of speed reading | Pronouncing words and increasing reading speed | Angle of view - an opportunity to learn to read zig-zag | Concentration - turning off extraneous noise Medication enhancers - how to increase the concentrating ability of the brain | Memorization - How to read, remember and not forget | Speed ​​reading course - for the busiest | Articles | Books and programs for downloading | Foreign language | Memory development | Typing with ten fingers | Drug-induced brain improvement | Feedback

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Picamilon - instructions for use

According to the instructions for use of Picamilon, the daily dosage of the drug ranges from 20–40 mg to 200–300 mg. It is divided into 2-3 doses and can be adjusted, depending on the type of disease and the degree of its activity. The course of treatment is long and lasts 1–2 months. After a break of 5–6 months, repeated therapy is possible.

How to take Picamilon: before or after meals

The medication is taken orally and by injection, regardless of food intake. The tablet is swallowed whole and washed down with a sufficient amount of water.

Comparison of addiction between Picamilon and Piracetam

Like safety, addiction also involves many factors that must be considered when evaluating a drug.

So, the totality of the values ​​of such parameters as “o syndrome” in Picamilon is quite similar to the similar values ​​in Piracetam. Withdrawal syndrome is a pathological condition that occurs after the cessation of intake of addictive or dependent substances into the body. And resistance is understood as initial immunity to a drug; in this it differs from addiction, when immunity to a drug develops over a certain period of time. The presence of resistance can only be stated if an attempt has been made to increase the dose of the drug to the maximum possible. At the same time, Picamilon has a fairly low “syndrome” value, just like Piracetam.

Picamilon analogs

The Russian pharmacological market is represented by a large number of Picamilon analogues in tablets and injections from different manufacturers, providing an equivalent therapeutic effect. Picamilon substitutes are sold in the form of:

• synonyms;
• combined agents;
• Generics.

They can be purchased either with a prescription or without a doctor's prescription.

Table of Picamilon analogues with price and country of origin

The price of Picamilon analogues has a wide range. Their cost depends on the manufacturer and raw materials. You can purchase drug substitutes on the recommendation of a doctor, both at a budget cost and at a higher price.

Picamilon or Mexidol - which is better and more effective?

Manufacturer: ELLARA LLC (Russia)
Release form: tablets, injection solution

Active ingredient: ethylmethylhydroxypyridine succinate

The drugs Mexidol and Picamilon are in different pharmacological groups, have different mechanisms of action, but equivalent treatment results. Picamilon will be better and more effective for older people with cerebrovascular insufficiency and other vascular diseases.

The drug dilates blood vessels, improves cerebral blood flow and reduces the manifestations of neurological symptoms. Under the influence of the medication, memory is restored and concentration increases. Its analogue will be the best for traumatic brain injuries and alcohol intoxication, since Mexidol has a greater antioxidant effect.

Drugs to improve memory and brain function - down with absent-mindedness and forgetfulness!

Drugs to improve memory and brain function are medications often prescribed by doctors when a person complains of poor memory.

They are well known to many older people: piracetam, Cavinton, nootropil, cinnarizine.

To improve brain function, medications are divided into 2 large groups:

The first includes vasodilators that improve cerebral circulation.

The second is nootropic drugs that increase metabolism in brain neurons.

You need to take one drug from each group at a time to improve memory.

It is with this combination of medications that brain function can improve as much as possible.

Medicines from the NOOTROPICS group to improve memory

Medicines that stimulate the brain are called “Nootropic drugs”. They differ in their mechanism of action.

However, the result from their use is the same - the intensity of metabolism in the neurons of the brain increases, neurotransmitters are produced that transmit nerve impulses along the pathways and energy in the form of ATP (adenosine triphosphoric acid).

The brain works more intensely, which means that memory and concentration are enhanced, performance, activity, mood levels increase, energy and productivity of brain processes increase.

Piracetam (nootropil)

The most popular, inexpensive, domestic product. It is what doctors most often prescribe when patients complain of poor memory. The drug is available in capsules, tablets and solution for injection in various dosages. Use 10-15 minutes before meals. The daily dose can be different - 1200-1800 mg. Treatment is carried out for at least 1-2 months.

Pantogam (pantocalcin)

This is also a Russian drug, prescribed for various disorders of the brain. Moreover, this may be a decrease in memory caused by chronic stress, psychosomatic disorders, as well as organic diseases (traumatic brain injury, vascular encephalopathy).

It is produced in tablet form (250 and 500 mg per tablet) and in the form of syrup for small children. The active ingredient is hopantenic acid, which enhances the synthesis of the neuromeliator gamma-aminobutyric acid (GABA).

Convulsive activity and excitability of the nervous system are suppressed, resistance to hypoxia and ischemia in brain tissue increases.

Aminolon (picamilon)

Produced in Russia. The active ingredient is GABA. It is an activator of metabolic processes, utilizes glucose, and removes toxins from cells. In general, thinking and memory improve, brain function is stimulated. Available in capsules or tablets of 250 mg. A safe medicine, it can be used by adults with heavy mental stress, and school-age children with poor memory.

Phenibut

This is also our domestic drug. The mechanism of action is to enhance the synthesis of GABA. But this medicine also has its own characteristics. It is only available with a doctor's prescription because it is a stronger drug.

It is used to restore the nervous system as a result of injuries and organic pathology of the brain. In addition to the stimulating effect, it has a pronounced sedative or calming effect.

Glycine

The drug is based on the amino acid glycine, which increases the activity of brain cells. Harmless product. It helps many people improve their memory, improve sleep, calm down, and increase the productivity of the nervous system. But there are also reviews in which people report that the drug did not help them at all.

Noopept

One of the new Russian drugs based on the action of glycine ethyl ester. It has a moderate nootropic and antihypoxic effect. Protects brain tissue from free radicals, toxins, hypoxia. Has a beneficial effect on cognitive functions and improves memory. Regulates autonomic functions and blood pressure.

Divaza

A new generation drug created by Russian scientists. The structure of the drug includes antibodies to the S-100 protein of brain tissue.

Promotes the creation of new integrative connections between brain neurons.

The result will be increased activity of the cortex, improved memory, thinking, and performance in case of neurosis, concussion, occupational hazards, and chronic fatigue syndrome.

Medicines for memory that improve cerebral circulation

If nootropics increase metabolism in cells and accelerate the conduction of nerve impulses, then vascular drugs have a neuroprotective effect through improving cerebral circulation.

Cinnarizine (Stugeron)

It has been used for many years as a means to increase cerebral blood flow. Indications for use are the initial manifestations of vascular atheroxlerosis. The drug can be used by elderly people with forgetfulness and poor concentration. The tablets are used for several months.

Cavinton (Vinpocetine)

Drugs to improve memory and brain function - microcirculation increases, blood viscosity decreases, and oxygen supply to the brain improves. Indications for use are chronic circulatory failure, impaired memory, intelligence, transient ischemic attacks, dizziness, hearing impairment, post-stroke conditions, and brain injuries.

Fezam

The medicine contains piracetam and cinnarizine. As a result of taking the combined drug, the cellular metabolism of brain tissue improves while simultaneously expanding the vascular system. Phezam is used for the initial forms of vascular atherosclerosis in relatively young people, in the elderly for complaints of poor memory, in adolescents with deterioration in learning ability.

Trental (agapurine)

Due to the active substance pentoxifylline, trental dilates cerebral vessels, enhances microcirculation, providing nutrition, oxygen, and energy to brain neurons. A similar effect is observed in the coronary and peripheral vessels. Like other vasodilators, trental restores and improves memory.

Ginkgo biloba (Tanakan, Memoplant)

Preparations based on extracts from Ginkgo biloba leaves are very widely used to improve memory by enhancing microcirculation, increasing the synthesis of adenosine triphosphoric acid (ATP), supplying tissues with oxygen, and reducing blood viscosity. The effect of the drug extends to the entire vascular system of the body: cerebral and coronary arteries, vessels of the extremities and internal organs.

Is it possible to take memory pills on your own, without consulting a doctor?

Can! Medicines to enhance memory are usually sold in pharmacies. Self-administration of medications to improve memory is allowed:

What memory medications can be given to young children?

You can notice memory problems in a young child by how he memorizes rhymes, how well he masters games with other children, and how he performs in kindergarten at holidays. At school, problems with learning and remembering become even more pronounced.

Never give your child any medications on your own or on the advice of friends. The causes of memory impairment should be determined by a pediatric neurologist. Treatment is carried out with the same medications as in adults.

In pediatric practice, it is recommended to use a limited list of nootropic drugs: Pantogam, Picamilon, Glycine, Cortexin, Semax, Sermion. More attention is paid to massage, osteopathy, therapeutic baths, and hardening.

A wide range of drugs to improve memory and brain function are presented on the pharmacological market. A small part of them can be taken independently if the reasons for its decrease are caused by mental overload, a chronic stressful situation at home or at work, or old age.

Source: https://polonsil.ru/blog/43192591057/Preparatyi-dlya-uluchsheniya-pamyati-i-rabotyi-mozga-%E2%80%93-doloy-ras

Picamilon or Pantogam - which is better and more effective

Manufacturer: OZONE LLC (Russia)
Release form: tablets, syrup

Active ingredient: hopantenic acid

Pantogam and Picamilon are nootropics that are part of the same drug group, but have a different mechanism of action. The Pantogam analogue also has an anticonvulsant effect. It will be best for adults suffering from senile dementia, epilepsy, mental illness with intellectual disabilities.

For children under 3 years of age, Pantogam will be more effective, since it is safer and can be used in newborns with perinatal encephalopathy. Picamilon will be the best for teenagers suffering from headaches or vegetative-vascular dystonia due to hormonal changes in the body.

Patient reviews of Nootropil

Alexey, 30 years old

I took Nootropil for about six months. It was prescribed to me due to constant headaches. I didn't expect any effect.

Maria, 24 years old.

When we studied at the institute, there were colossal workloads. My classmate recommended Nootropil - she drinks it herself and said that it has a good effect.

I carefully studied the instructions. The first day I felt unwell – dizzy, throbbing in my temples. On the second day the same effect. On the third I already decided to cancel. I'd better manage it myself somehow.

Picamilon or Cavinton - which is better?

Manufacturer: JSC GEDEON RICHTER (Hungary)
Release form: tablets, solution concentrate for injection

Active ingredient: vinpocetine

Cavinton and Picamilon have different active substances and mechanisms of action, but equivalent indications. For vascular disorders of a central nature, Cavinton will be the best. This analogue has a pronounced vasodilating effect.

This effect of the drug leads to an improvement in cerebral blood flow, a decrease in blood viscosity and the prevention of blood clots. The improvement in neurological symptoms is confirmed by reviews of patients receiving treatment with the imported analogue of Picamilon.

Indications and contraindications

Indications for the use of nootropil are as follows:

• vestibular disorders and dizziness;
• symptomatic treatment of intellectual impairments and memory disorders, if there is no reason to suspect dementia;
• involuntary twitching of muscle mass (cortical myoclonus);
• speech problems in children;
• prevention of vaso-occlusive sickle cell crisis: the development of thrombosis provoked by a genetic abnormality in the cellular structure of hemoglobin.

The negative aspects of the drug include:

• the presence of a higher dose of the active component than in its analogue;
• piracetam, taken in a dosage greater than 9.6 g per day, provokes an increase in the effectiveness of acenocoumarol in patients diagnosed with venous thrombosis (in this condition there is a strong decrease in platelet aggregation, plasma and blood viscosity, fibrinogen level);
• the impossibility of abruptly stopping the medication due to increased manifestations of the disease or its resumption.

Picamilon or Piracetam - which is better?

Manufacturer: JSC SINTEZ (Russia)
Release form: tablets, capsules, injection solution

Active ingredient: piracetam

Piracetam and Picamilon are nootropic drugs that improve cognitive impairment due to hypoxia or intoxication. The Piracetam analogue will be the best for vascular lesions of various origins.

A special feature of Piracetam is its ability to penetrate and concentrate in the area of ​​ischemia. The drug stimulates local metabolism, microcirculation and reduces blood viscosity. For children, Picamilon will be the best, since the medication is safer, increases the child’s mental abilities and has fewer side effects.

Comparison of the safety of Picamilon and Piracetam

The safety of a drug includes many factors.

At the same time, in Picamilon it is quite similar to Piracetam. It is important where the drug is metabolized: drugs are excreted from the body either unchanged or in the form of products of their biochemical transformations. Metabolism occurs spontaneously, but most often involves major organs such as the liver, kidneys, lungs, skin, brain and others. When assessing the metabolism of Picamilon, as well as Piracetam, we look at which organ is the metabolizing organ and how critical the effect on it is.

The risk-benefit ratio is when the prescription of a drug is undesirable, but justified under certain conditions and circumstances, with the obligatory observance of caution in use. At the same time, Picamilon does not have any risks when used, just like Piracetam.

Also, when calculating safety, it is taken into account whether only allergic reactions occur or possible dysfunction of the main organs. In other matters, as well as the reversibility of the consequences of using Picamilon and Piracetam.

Picamilon or Phenibut - which is better and more effective, what is the difference

Manufacturer: JSC ORGANIKA (Russia)
Release form: tablets

Active ingredient: aminophenylbutyric acid

Phenibut and Picamilon have a nootropic effect and are in the same pharmacological group, but act on the body through different mechanisms. The difference between the drugs is:

• The release form is Picamilon in tablets and ampoules, and its analog Phenibut is only in tablets.
• Composition of main and auxiliary ingredients.
• Vasodilator effect - Picamilon dilates blood vessels, but Phenibut does not.
• Possibility of developing addiction - long-term therapy with Phenibut can provoke addiction.
• The advantage of the effect is that Phenibut is more effective as a tranquilizer, and Picamilon as a nootropic.

According to patient reviews, Phenibut copes well with asthenia, insomnia, anxiety, unmotivated fear and will be the best for psychosomatic diseases accompanied by these symptoms.

Comparison of side effects of Picamilon and Piracetam

Side effects or adverse events are any adverse medical event that occurs in a subject after administration of a drug.

Picamilon has almost the same side effects as Piracetam. They both have few side effects. This implies that the frequency of their occurrence is low, that is, the indicator of how many cases of an undesirable effect of treatment are possible and registered is low. The undesirable effect on the body, the strength of influence and the toxic effect of Picamilon are similar to Piracetam: how quickly the body recovers after taking it and whether it recovers at all.

Picamilon or Vinpocetine - which is better?

Manufacturer: OZONE LLC
Release form: tablets, injection concentrate

Active ingredient: vinpocetine

These drugs are in different groups, have different mechanisms of action, but similar treatment results. Vinpocetine is a drug that improves cerebral blood flow. This is achieved through a vasodilating effect, reducing blood viscosity, stimulating cellular respiration and the uptake of glucose by brain cells.

Vinpocetine will be best for cerebrovascular pathologies, and Picamilon - for migraines, alcohol intoxication, neurotic conditions (irritability followed by an apathetic state, sleep disturbance).

Patient reviews of Noopept

Alla, 67 years old.

Forgetfulness and absent-mindedness are familiar to me firsthand. I could read the same book for weeks because I would forget that I had just read it. The children brought Noopept. I didn’t really believe it myself, but since the children were already taken care of, I decided to try it. After two weeks, I felt that I became more active, my sleep improved, and I became calmer. And after some time the memory returned to normal.

Semyon, 32 years old

I work as a department head. You have to solve a lot of issues, keep a thousand little things in your head. He became irritable, anxious, and had problems sleeping. My wife started giving me some pills at breakfast and asked me to drink it around six. I noticed that I felt much better. I feel calmer and more confident. And, most importantly, no feelings of “fogginess” or brain overload. Then I looked at the box - the medicine “Noopept”.

Picamilon or Aminalon - which is more effective?

Manufacturer: JSC ORGANIKA (Russia)
Release form: tablets, capsules

Active ingredient: gamma-aminobutyric acid

Both drugs have nootropic properties, that is, they improve the functions of higher nervous activity (memory, analysis, learning). Medicines are based on gamma-aminobutyric acid. But the active substance analogue of the drug Picamilon does not contain nicotinic acid, which affects the properties of Aminalon.

Picamilon will be more effective, since, thanks to this inclusion in the active ingredient, the drug acquires a better vasodilator and nootropic effect.

Comparison of the effectiveness of Picamilon and Piracetam

The effectiveness of Picamilon is quite similar to Piracetam - this means that the ability of the drug to provide the maximum possible effect is similar.
For example, if the therapeutic effect of Picamilon is more pronounced, then using Piracetam even in large doses will not achieve this effect.

Also, the speed of therapy - an indicator of the speed of therapeutic action - is approximately the same for Picamilon and Piracetam. And bioavailability, that is, the amount of a drug reaching its site of action in the body, is similar. The higher the bioavailability, the less it will be lost during absorption and use by the body.

Picamilon or Cinnarizine - which is better?

Manufacturer: JSC BIOSINTEZ (Russia)
Release form: tablets

Active ingredient: cinnarizine

Cinnarizine and Picamilon are drugs from different pharmacological groups and different actions, which have a vasodilating effect and are used for vascular pathologies of various etiologies. Picamilon will be better than its analogue: it more effectively stimulates blood supply to the brain, which leads to increased blood flow and a decrease in the clinical manifestations of vascular insufficiency.

Under the influence of the drug, vascular resistance decreases, blood rheological properties (viscosity) improve, and microcirculation is stimulated.

Comparison of ease of use of Picamilon and Piracetam

This includes dose selection taking into account various conditions and frequency of doses. At the same time, it is important not to forget about the release form of the drug; it is also important to take it into account when making an assessment.

The ease of use of Picamilon is approximately the same as Piracetam. However, they are not convenient enough to use.

The drug ratings were compiled by experienced pharmacists who studied international research. The report is generated automatically.

Last update date: 2020-12-04 13:47:59

Picamilon or Actovegin - which is better?

Manufacturer: NYCOMED GMBH (Austria)
Release form: tablets, injection solution, cream, ointment, gel for external use

Active ingredient: deproteinized hemoderivative of calf blood

Both drugs have different active substances and mechanisms of action, but have equivalent indications and are used for vascular diseases. Actovegin will be the best, as it has broader indications.

The medication provides a therapeutic effect not only for vascular pathology of the central nervous system, but also for diseases of the peripheral nervous system, lesions of the skin and mucous membranes. It is easier to tolerate by patients, gives a quick effect and has an injection form of administration.

Which drug is best for whom?

The presented nootropics occupy leading positions in the list of prescribed neuroprotectors. This is facilitated by a good therapeutic effect and low toxicity.

According to reviews from doctors and patients, Piracetam is indispensable for ensuring the smooth flow of metabolic processes in the central nervous system during stress. Helps cope with vascular lesions of the brain, especially those caused by natural aging of the body.

Picamilon will help to quickly restore decreased performance, both physical and mental, if it is caused by overwork or stress factors. It fights well against chronic alcoholism.

The minimum side effects allow it to be prescribed to children more often than Piracetam.

However, only a qualified doctor can competently say which medicine is better, and even more so to whom and when to prescribe it.

When prescribing medications, the doctor takes into account the severity of the pathology, the patient’s age, the presence of concomitant diseases, and specific contraindications.

Nootropics are serious drugs. Their appointment is prescribed by a specialist and is carried out under his supervision. Self-medication with any of the drugs can lead to irreversible consequences for the body.

Cortexin

Manufacturer: GEROPHARM LLC (Russia)
Release form: powder for the preparation of a solution for intramuscular administration

Active ingredient: polypeptides of the cerebral cortex of cattle

Cortexin is a nootropic drug and contains a complex of polypeptide fractions that has a direct effect on nerve cells, penetrating their structure. This analogue of Picamilon injections improves and restores impaired cognitive disorders (memory, attention), increases resistance to stress, and stimulates the metabolism of nervous tissue.

Piracetam: description of the drug

This nootropic is designed to regulate metabolic processes in the brain, improve blood circulation, saturate cells with oxygen, and stabilize its general condition.

Piracetam is a single drug containing the active ingredient of the same name.

The medicine is released in the following format:

1. Coated tablets, white, convex on both sides. The tablet contains 200 or 400 mg of the active ingredient.
2. Capsules, red-white or black-white, containing 400 mg of active substance.
3. Ampoules of 5 ml, with 20% injection solution.

Excipients: polyvinyl alcohol, calcium stearate, polyvinylpyrrolidone, talc, iron oxide.

Capsules contain: gelatin, sodium lauryl sulfate, azorubine dye, silica, methyl parahydroxybenzoate, titanium dioxide.

Injection solutions are supplemented with sodium salt, diluted acetic acid, and distilled water.

Piracetam is prescribed for the following pathologies:

• Atherosclerosis.
• Viral neuroinfections.
• Vestibular nystagmus.
• Alzheimer's disease.
• Epileptic seizures.
• Dizziness.
• Psychoorganic syndrome.
• Decreased intellectual functions.
• Chronic alcoholism.
• Sluggish schizophrenia.
• Depressive states.
• Ischemic stroke (recovery stage).
• Cortical myoclonus, etc.

Pediatricians also did not ignore Piracetam. It is used for mental retardation, cerebral palsy, mental retardation, low learning ability and other psychoorganic pathologies.

Glycine

Manufacturer: BIOTIKI LLC (Russia)
Release form: tablets

Active ingredient: glycine

Glycine belongs to the group of neurotropic drugs and is a metabolic regulator. The medication reduces the manifestations of neurological symptoms during a stroke, reduces psycho-emotional stress, and normalizes sleep.

The drug is effectively used in pediatric practice to stimulate the mental development of children and improve the learning ability of schoolchildren.

Cytoflavin

Manufacturer: POLYSAN LLC (Russia)
Release form: tablets, injection solution

Active ingredient: inosine, nicotinamide, riboflavin, succinic acid

Cytoflavin is a combination drug that has a metabolic effect with a high degree of bioavailability.

The medication improves the function of interstitial respiration and metabolism in the cells of the central nervous system, stimulates protein biosynthesis and eliminates cognitive disorders.

What else can replace Picamilon, what effective drugs that improve the functions of the central nervous system?

You can supplement the list of medications by the following means:

• A nicotinic acid:
• Nootropil;
• Encephabol:
• Pentoxifylline;
• Cerebrolysin;
• Noopept;
• Ceregamon;
• Afobazole;
• Anvifen;
• Vasobral;
• Mildronate;
• Betahistine;
• Cereton;
• Ceraxon;
• Ginko biloba;
• Lutsetam;
• Sermion;
• Noben;
• Gammalon;
• Phezam.

Among these substitutes there are analogues of Picamilon for children, which are widely used in pediatric practice.

A properly selected analogue of Picamilon 50 mg will make it possible to stimulate cerebral blood flow in cerebral insufficiency of various origins, improve the functions of the central nervous system and prevent further development of the disease.

What's better

We cannot say that one drug is better than another. Both drugs are effective in restoring brain function. The choice of one or the other is made individually, based on the degree of impairment of cognitive indicators, causes and capabilities of the body.

Picamilon is best used for severe impairments of attention, memory, speech and motor abilities after a stroke. It is preferable for patients prone to anxiety and depression. For long-term therapy of patients whose work is associated with mental or physical overload, stress. Cavinton is more useful if the patient is bothered by dizziness, noise in the head or ears. Not recommended for arrhythmias, severe cardiac ischemia.

Both drugs are contraindicated in pregnant and breastfeeding women. Should be taken with caution in case of renal and liver failure.

Answers on questions

Is Picamilon an antidepressant or not?

No, the medication is a nootropic that acts on the vascular system.

Does Picamilon Increase or Lower Blood Pressure?

The drug has a vasodilating effect, which leads to a decrease in blood pressure.

Should Picamilon be dissolved or swallowed?

Picamilon tablets should be swallowed and washed down with plenty of water.

Does Picamilon thin the blood or not?

Yes, the medication thins the blood and prevents the formation of blood clots.

Does Picamilon have a cumulative effect or does it work immediately?

The drug acts immediately and does not have a cumulative effect.

Are Picamilon injections painful or not?

IM injections of Picamilon cause minor pain.