Grandaxin: instructions for use of the drug

Composition and release form

The medicine is dispensed in the form of tablets for oral administration. Externally, they are white or have a slight gray tint, and are flat in shape. There is a risk and an unexpressed odor. Packaged in blisters of 10 pieces. One cardboard box contains 2 or 6 blisters with attached instructions for use.

The active ingredient is tofisopam in an amount of 50 mg.

Additional substances: talc, gelatin, potato starch, lactose, magnesium stearate, stearic acid.

pharmachologic effect

Grandaxin is an effective tranquilizer that helps relieve symptoms of fear and anxiety in various psychological and autonomic disorders. It also has a stimulating property. It can be prescribed to patients with myopathies and myosthenia. The drug does not have any dependence; upon completion of the treatment course there is no withdrawal syndrome. Is a daytime remedy.

After oral administration, it is instantly absorbed by the gastrointestinal tract and the active components are absorbed into the bloodstream. The highest concentration of Grandaxin occurs after 2 hours. Most of it is excreted in urine and the rest in feces.

Tranquilizers against panic attacks

Tranquilizers are also called anxiolytic drugs. These drugs have a good anti-panic effect, so they are widely used in psychotherapy.

Popular tranquilizers for panic attacks:

1. Afobazole, intended for a course of treatment of at least a month. Only in this case is the necessary therapeutic effect achieved: new attacks stop bothering the patient. An important advantage of this drug is that it does not reduce the ability to concentrate and does not cloud a person’s consciousness. Such side effects are common to many other tranquilizers.
2. Lorazepam is a medicine for both panic attacks and phobias. Before taking it, you need to take into account its hypnotic effect. The course of treatment ranges from 45 to 60 days.
3. Grandaxin for panic attacks copes well with manifestations of anxiety and fear. Reviews about this drug are mostly positive. For many patients, the absence of drowsiness and addiction to the drug is a plus. It can be used during the daytime, at work, etc.

Lorazepam helps fight panic attacks and phobias

Anxiolytics are taken both at the time of an attack and for long-term drug therapy, with the goal of preventing repeated episodes of the disease.

What does Grandaxin help with?

The main indications for use of the product are:

1. The period before the onset of menopause.
2. Pain in the heart.
3. ​Violation of psychological adaptation.
4. ​Severe premenstrual syndrome.
5. Neuroses of any origin.
6. ​Myasthenia and myopathy.
7. ​Vivid clinical picture after withdrawal of alcoholic beverages.
8. Nervous states - constant excitement, anxiety, apathy, fear, causeless worries.
9. Vegetative-vascular dystonia.

How does VSD manifest?

VSD develops against the background of chronic or acute diseases. You should be wary if the following signs appear:

• gastrointestinal disorders, accompanied by bloating, nausea, increased gas production, diarrhea;
• changes in breathing, a feeling of lack of air, more rapid breathing, which causes hyperventilation;
• heart pain, tachycardia, high blood pressure;
• violation of thermoregulation, increased sweating;
• sexual dysfunction, manifested in painful menstruation and lack of orgasm.

Contraindications

Prohibited conditions for taking a tranquilizer are:

1. ​Frequent apnea at night.
2. ​Serious form of respiratory failure.
3. ​Individual intolerance to the active or auxiliary components.
4. ​The first 3 months of bearing a child and the period of breastfeeding.

The drug contains lactose, so patients suffering from deficiency or intolerance to this substance should not use the medicine.

Grandaxin is prescribed with caution to patients with glaucoma, epilepsy attacks, atherosclerosis and respiratory failure.

Causes of VSD

VSD can cause malfunction of any organ. The appearance of most diseases is associated with impaired vascular tone.

The most common causes of VSD development are:

1. Cardiovascular diseases;
2. Endocrine system disorders;
3. Allergic diseases;
4. Violation of intestinal microflora;
5. Pathologies of the liver, gall bladder and bile ducts;
6. Gastritis, colitis, ulcers;
7. Osteochondrosis;
8. Bad habits;
9. Sedentary lifestyle.

Side effects

Treatment with the drug may cause the following side effects:

1. ​Dyspeptic symptoms - nausea, constipation, flatulence, loss of appetite, dry mouth and signs of jaundice.
2. ​Pain in the muscles.
3. Allergic reactions - itching, skin rash, exanthema, urticaria.
4. ​Headache, confusion, sleep disturbance, symptoms of irritability, increased agitation.

VSD classification

Depending on which organ system the disease affects, there are several types of VSD:

1. Cardiac VSD – characterized by pain in the left side of the chest, tachycardia;
2. Thermoregulatory VSD is a violation of heat exchange, body temperature is constantly changing;
3. Respiratory VSD – symptoms similar to asthma appear, constant shortness of breath;
4. Genitourinary VSD – the appearance of pain during urination in the absence of organ pathology;
5. Dysdynamic VSD – blood flow disturbances, changes and sudden surges in pressure;
6. Dyspeptic VSD – disorders of the gastrointestinal tract, diarrhea, vomiting;
7. Psychoneurological VSD - characterized by anxiety, insomnia, fatigue, sensitivity to weather changes.

Interactions with drugs

You cannot combine Grandaxin with Cyclosporine, Tacrolimus and Sirolimus.

The simultaneous use of the drug with sleeping pills, antidepressants, sedatives, painkillers and antipsychotic drugs leads to an increase in the sedative effect of the latter.

Alcoholic drinks and nicotine provoke rapid decomposition of the medicine. Therefore, the concentration of the main substance decreases and the therapeutic effect is suppressed.

Some antifungal pharmacological drugs interfere with the normal metabolism of Grandaxin, contributing to an increase in its level in the blood.

The effectiveness of the active substance is enhanced by Clonedin and calcium channel antagonists.

Drug treatment for panic attacks

Treatment of anxiety disorders is the task of a psychotherapist. To help the patient, you need to find the root of the problem, that is, the reason that triggered the appearance of panic attacks. Psychological problems play an important role: stress, complexes, unpleasant experiences, etc., therefore psychotherapy sessions are the foundation of treatment. The use of medications successfully complements them, especially in severe cases.

Worth seeing: Reviews of Phenibut for panic attacks

Only a qualified specialist can decide how to treat panic attacks and which pharmacological groups of drugs should be used. Amateur activities can lead to a deterioration in the general condition and dangerous side effects on the human body.

All medications used to treat panic attacks are divided into several groups:

1. Remedies for relieving panic attacks that act with lightning speed. These are benzodiazepines, classified as tranquilizers. They show good results, but frequent use leads to addiction and side effects: lethargy, drowsiness, and decreased concentration. Therefore, it is advisable to use them only in extreme cases. These are tablets and injections containing diazepam, midazolam, temazepam.
2. Other types of tranquilizers for the course of treatment;
3. Antidepressants;
4. Neuroleptics, which have a general calming effect on the body during a panic attack;
5. Beta blockers that lower blood pressure and pulse. They, like benzodiazepines, are used for anxiety attacks.
6. Nootropics, which include the well-known glycine. They usually play a supporting role in therapy because they normalize blood supply to nerve tissues, metabolism and oxygen saturation of cells. All this helps the brain work better.

You can fight panic attacks with antidepressants

Herbal-based sedatives are also used for panic attacks. These are tablets, syrups, mixtures and tinctures, which are sold in a wide range in pharmacies. Valerian, motherwort, and lemon balm reduce the level of anxiety. But their use is indicated either as an adjuvant in treatment with more serious medications, or in mild forms of psychological disorders.

Special instructions for the medication

The development of adverse reactions is often observed in patients suffering from severe pathologies of the kidneys, liver, mental disorders, and also in elderly patients.

It is not recommended to take pills for psychoses, various phobias and obsessive states. In this case, there may be a tendency towards suicide and aggressive behavior.

The tranquilizer does not impair concentration and mental activity, therefore it is not prohibited to independently drive a vehicle during the treatment course.

Compared to analogues

If there is no effect from treatment with Grandaxin or negative reactions appear, then it is worth considering the possibility of selecting an analogue. The first criterion should be safety, since this drug is considered relatively harmless. An almost complete analogue of the main active ingredient of the drug is Tofisopam. In terms of effects, there are the following analogues: “Afobazol”, “Phenibut”, “Adaptol”, “Atarax”, “Tenoten”, “Phenazepam”.

Most often, Grandaxin is replaced with Afobazol. It has fewer side effects, but the price is higher. Phenibut, in contrast to the stimulating effect of tofizopam, causes drowsiness. It is used before exciting events. Can be used for insomnia and increased excitability as a strong sedative.

Adaptol, like Grandaxin, is a daytime tranquilizer. May cause sleep disturbances. Its effect is slightly weaker, but accumulates with prolonged treatment. "Atarax" in addition to the sedative has a bronchial stimulating effect. If you have respiratory depression, Grandaxin should not be taken. "Atarax" can also be used by patients with kidney and liver pathologies. But it has more contraindications: lactose allergy, pregnancy, galactose intolerance. "Tenoten" is a homeopathic remedy with a sedative effect and a small number of adverse reactions. Its effect is much weaker than that of Grandaxin. "Tenoten" is used in pediatrics.