Features of the formation of plaques in blood vessels: causes and methods of treatment

What are cholesterol plaques

This pathology does not form immediately. In medicine it is called atherosclerosis. This is a disease that affects the cardiovascular system. The formation of plaques does not occur immediately. There are several steps before this.

Due to poor diet, which contains plenty of animal fats, cholesterol levels begin to increase.

Total cholesterol in the blood has several fractions:

  • HDL is a high-density lipoprotein that is responsible for the structure of cells, the production of sex hormones and the transport of excess cholesterol to the liver for its further removal from the body;
  • VLDL – very low density lipoproteins, responsible for the delivery of triglycerides from the liver to all tissues of the body;
  • LDL are low-density lipoproteins that appear during the synthesis of the previous fraction.

The first category of lipoproteins is considered “good” cholesterol, the last two are considered “bad”, since they have the ability to accumulate in the body, do not dissolve in water and are deposited on the walls of blood vessels.

The more a person eats poorly, the higher the concentration of LDL in the body. Excess cholesterol settles on the walls of blood vessels, forming atherosclerotic plaque. With the development of pathology, the formation of atherosclerotic plaques occurs.

At first they have a liquid structure and are still capable of dissolving. But, over time, they are replenished with deposits of calcium salts, which is why the plaques in the vessels acquire a more dense structure.

The situation is constantly getting worse if appropriate measures are not taken.

Cholesterol plaques can break off and, passing through the bloodstream, attach to injured areas of blood vessels, narrowing their lumen. All this leads to the formation of blood clots, which pose a very great danger to the entire body.

Simple recipes

  1. Chop a medium-sized head of garlic, pour in 700 milliliters of Cahors wine. After standing in a dark place for two weeks, take 20 milliliters three times a day.
  2. Mix garlic juice with honey in the same proportion. Forty minutes before meals, take one tbsp. spoon. The course of treatment is thirty days.
  3. Add a quarter teaspoon of garlic to half a glass of goat milk. Taken in the morning on an empty stomach, daily.
  4. Chop the head of garlic and add a glass of unrefined sunflower oil. Leave for a day and add juice from one lemon. Continue to leave in a cool place for a week. Take a teaspoon three times a day.
  5. Mix the garlic pulp with the same amount of walnuts and olive oil. Add to salads daily. Keep refrigerated.
  6. Onion syrup. Pass a large onion, weighing more than one hundred grams, through a meat grinder and add half a glass of sugar. Insist for a day. Take 20 grams an hour after meals, up to four times a day.
  7. Mix onion juice with honey in a ratio of 2 to 1. Take a spoon three times a day.

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Signs of atherosclerosis

The main problem of this disease is that it remains asymptomatic for a long time. The problem begins with the appearance of lipid stains. They are so small that they can only be seen under a microscope.

Naturally, this does not affect your well-being in any way. Developing further, plaques form in the vessels. But when these growths are small, a person also does not feel them at all. And only when atherosclerotic plaques become large-scale, when blood clots are already forming, then a person feels obvious signs of the disease.

Therefore, it is necessary to undergo a special biochemical blood test to check cholesterol levels at least once a year.

Having received detailed lipid profile indicators, the doctor is able to track not only increased or decreased values ​​of total cholesterol levels, but also track the indicators of all its fractions in relation to each other. This will allow you to track the problem in time at a stage when everything can still be solved with a simple nutritional correction.

But if the disease is already advanced, then the symptoms of atherosclerosis will depend on its location.

Main symptoms

Symptoms of atherosclerosis do not appear immediately, although the disease progresses within the body. The condition of the atherosclerotic plaque becomes unstable due to the following systemic factors: constant physical activity, stress and depression, cardiac dysfunction and hypertension. Blood clots may form on the surface of the weakened plaque, which will aggravate the disease. High risk of heart attack and stroke. In this case, the symptoms will be clearly expressed.

Atherosclerosis is dangerous because it can be a harbinger of fatal diseases:

  • Stroke.
  • Heart diseases, including myocardial infarction.
  • Atherosclerosis of the renal and mesenteric arteries.

People who have had a stroke may face the same serious problems in the future. The fact is that their peripheral arteries are affected, and therefore there is a high risk of developing a heart attack.

Atherosclerosis of the aorta of the heart poses a huge danger. This disease manifests itself in people who have reached the age of sixty. In this case, the main symptom is very severe pain in the chest. Moreover, in some cases they can radiate to the back and neck. If a person experiences stress or constant nervous tension, then these pains only intensify. They may not subside for several days, and people often have to take analgesics and other pain relievers.

The following symptoms may also appear:

  • Problems with the gastrointestinal tract (bloating, constipation, abdominal pain).
  • Swallowing disorder.
  • Severe weakness due to systematic dizziness.
  • Impotence.
  • The onset of lameness, coldness of the lower extremities.

If you do not see a doctor on time, the disease can get much worse. There are often cases when ignoring the disease led to rupture of the aorta, which ended in death. Therefore, doctors who know what it is - atherosclerosis of the aorta of the heart, recommend starting treatment immediately. The disease itself does not weaken, but only intensifies, especially if a person leads an incorrect lifestyle.

The main symptom of atherosclerosis of the renal arteries is a significant change in urine parameters. You need to get tested for the doctor to confirm or refute the diagnosis. If the disease really exists, then the patient experiences constant high blood pressure.

The main symptom of atherosclerosis of the mesenteric vessels is severe pain in the abdominal area. It usually appears while eating. Symptoms such as serious bowel dysfunction, bloating and other gastrointestinal problems also appear. The causes of atherosclerosis in this case are not so important; first of all, competent treatment is necessary!

Finally, about the symptoms of atherosclerosis of peripheral arteries. It manifests itself as severe weakness of the leg muscles. A person feels serious discomfort while walking, and lameness may appear. In some cases, the pain in the limbs is so severe that the patient is forced to take some pauses while moving.

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Symptoms of cerebral vasoconstriction

The most dangerous are cholesterol deposits in the blood vessels of the brain. They are the least treatable and most endanger a person’s life.

If plaque growths are significant, the patient may experience:

  • Severe migraines;
  • Frequent dizziness;
  • Insomnia;
  • Increased anxiety;
  • Psychical deviations;
  • General mental instability.

In the advanced course of the disease, mental instability manifests itself in insensitivity to new information, poor memory and the inability to self-care. At this stage of development, the disease is virtually untreatable.

Stages of development

Stage 1 of atherosclerotic plaque formation.

The formations characteristic of this stage occur in the form of compaction on the endothelium of the artery.

The first stage has a long period of tumor growth. There are no symptoms of the presence of a cholesterol tumor in the bloodstream.

It is practically impossible to diagnose the development of atherosclerosis at this stage, because a person does not go to the doctor due to the absence of signs of the formation of atherosclerotic plaques.

Stage 2 of development of sclerotic neoplasms.

Occurs at this stage of increasing compaction, but this process is also quite slow.

Cholesterol accumulations partially begin to blow out above the surface of the artery and block the lumen.

At the second stage, soft lipid deposits can already be diagnosed using instrumental diagnostic methods and the disease can be cured completely without changing the arterial membrane.

Stage 3 of the formation of atheromatous neoplasms.

At this stage, the soft structure of the atherosclerotic plaque is still preserved, which is dangerous due to its ruptures and the development of artery blockage, or complete occlusion of the plaque.

The third stage of development of cholesterol plaques is fraught with the development of unstable angina, cerebral stroke, myocardial infarction, gangrene of the lower extremity, as well as the development of thrombosis pathology in various parts of the bloodstream system.

At this stage, there are pronounced symptoms of the development of pathology, which has a rapidly progressive form. The specific course of the pathology of atherosclerosis depends on the localization of the atherosclerotic plaque, on its shape and structure.

Stages of plaque formation

Separation by type

Atherosclerotic plaques of low stability.

Cholesterol deposits on arterial walls form a plaque homogeneous in structure, which is no denser than blood plasma.

This form is unfavorable because it has a rapid growth rate of the tumor and is most often the cause of the development of atherosclerosis in the coronary arteries and coronary insufficiency.

Neoplasms of low stability cannot be diagnosed at the initial stage of development; pathology is detected already at the first signs of coronary insufficiency.

Atheromatous plaques of moderate stability.

These plaques are cholesterol neoplasms, loose in structure, covered with a membrane of fibrous tissue that has the ability to rupture and form a blood clot, which is transported through the bloodstream and blocks the arterial lumen.

Neoplasms are of average stability and do not contain calcium molecules, so they respond well to drug and non-drug therapy.

Atherosclerotic plaques of high stability.

The plaque shell consists of collagen fibers and has an elastic shape.

The growth of this plaque occurs quite slowly, but with confident stability. With slow and stable growth, the calcification phase of the cholesterol neoplasm occurs.

A calcified neoplasm makes correct diagnosis difficult, due to the fact that the plaque is located under a dense layer of calcified formation. For this reason, it is impossible to see the condition of the tissues around the plaque location and the structure of the tissue. This makes it difficult to properly assess arterial stenosis and atherosclerosis pathology.

According to their structure, neoplasms differ in the following types:

  • Homogeneous type is a homogeneous lipid compaction that does not contain vascular bundles and has a smooth surface;
  • A heterogeneous atherosclerotic plaque is a neoplasm with numerous growths and a loose structure. This type of plaque has the properties of a permanent expression.

Based on the types of atherosclerotic plaques, as well as their types, treatment methods, both medicinal and non-medicinal, are developed.


Stable atherosclerotic plaque

Symptoms of vasoconstriction in the legs

The main symptom of this localization is intermittent claudication. This is a condition in which, while walking, a person is forced to stop, shifting from foot to foot, in order to relieve pain.

With the development of atherosclerosis of the lower extremities, the color of the skin on the legs, especially on the feet, changes. It takes on a bluish tint. Feet are constantly cold, even when it’s warm a person always puts on warm socks.

As it progresses, painful sensations appear in the legs, even if they are at rest. The patient can no longer lie down for a long time, but by lowering his legs down, on the contrary, he experiences relief.

The most severe symptoms are signs of an advanced stage - necrosis of individual tissues of the legs, in which there is no blood supply and the tissues die. Trophic ulcers develop, and gangrene of the feet may form.

Symptoms of cervical vasoconstriction

The vessels of the cervical spine provide a complete supply of oxygen and nutrients to the vessels of the entire head. Therefore, the formation of plaques in them is very dangerous.

The symptoms are very striking, since with this localization the entire brain suffers:

  • The initial sign is a feeling of discomfort and stiffness in the cervical spine;
  • Then frequent dizziness begins to develop;
  • All this provokes a further loss of strength and a general deterioration in well-being;
  • Then memory deteriorates.

The insidiousness of the disease is that a person gradually gets used to pain in the neck, ceasing to pay attention to it. This further increases the risks, since, over time, the likelihood of thrombosis and complete blockage of blood vessels develops. Thus, affecting an important vessel, a blood clot often provokes death.

Methods for diagnosing cervical plaques

When you first contact a therapist with the symptoms described above, first of all, the doctor will prescribe a test that will reveal the cholesterol content and a detailed study of all its fractions. This testing is called a lipid profile.

If the results of this diagnostic do not clearly exceed the normalized values, then this can be limited. But if the indicators are greatly overestimated, then an experienced specialist will understand that, most likely, the disease is already in advanced stages, when cholesterol plaques appear.

Research is possible only when they are already clearly visible. This means that the situation has started.

Therefore, for the purpose of preventive examination, it is necessary to take blood biochemistry annually, or perform a basic test to detect cholesterol levels using a portable analyzer.

In modern life, in order to monitor your health, you do not need to spend a lot of time, effort and money. And even if preventive studies are paid, they are quite accessible to the average class.

If deviations from the norm are detected, the therapist may then prescribe additional examinations for:

  • Surgeon;
  • Neurologist;
  • Cardiologist;
  • Nephrologist;
  • Nutritionist.

The following tests serve as laboratory and instrumental diagnostics:

  • CBC and blood biochemistry;
  • OAM;
  • CT;
  • MRI;
  • ECG;
  • Vascular ultrasound.

The last type of analysis is the most promising in the study of atherosclerotic plaques of the cervical vessels. But, as already mentioned, their exact identification is determined when the lumen is either very narrowed or completely closed.

Diagnostics

The diagnostic scheme is as follows:

  • Examination of the patient.
  • Anamnesis collection.
  • Laboratory blood tests.
  • Instrumental methods: Vascular ultrasound (duplex scanning and triplex scanning) gives an idea of ​​the blood flow and structure of blood vessels; X-ray of the aorta allows you to determine calcification, expansion of the aortic window, and aneurysm; angiography is an x-ray examination of blood vessels with the introduction of a contrast agent.

When diagnosing cholesterol plaques, it is important to distinguish them from other pathologies:

  • with atherosclerosis of cerebral vessels - from head injuries, neurasthenia, cerebral syphilis and others;
  • with damage to the aorta - from diseases of the digestive system and abdominal organs;
  • for blockage of blood vessels in the legs - from varicose veins, conditions after injuries and others.


Angiography allows you to identify atherosclerotic plaques, determine their size and location

How the presence of plaques affects the patient’s face

The most obvious manifestation on the face of the presence of plaques in blood vessels is xanthelasma. These are benign neoplasms in the form of yellowish sacs that appear in the eyelid area. They will never turn into a malignant form, but they will not go away on their own.

Xanthelasmas appear as a result of increased cholesterol levels, and, as a result, the formation of atherosclerotic plaques. Doctors often suggest getting rid of these tumors through removal.

But deletion alone will not fundamentally solve the problem. Xanthelasmas will appear again if the vessels are not cleaned and the cause of their appearance is not eradicated.

New growths are not only capable of returning, but also uniting with each other. When several xanthelasmas unite during the process of growth, this phenomenon is called xanthoma.

How does atherosclerosis occur?

First, deposits of LDL cholesterol appear in the intima of the vessel wall. They oxidize and a local inflammatory reaction occurs. Monocytes migrate into the tissue and phagocytose cholesterol. After which plaques with a high content of cholesterol and lipids are formed. These atherosclerotic lesions are called fatty streaks and occur in areas of high mechanical stress (at the ruptured interventricular portion or carotid bifurcation).

Subsequently, more and more LDL and macrophages are deposited, which leads to the release of biologically active substances. Lipids accumulate and cell death in the intima is observed. Various cells of the vessel wall release mediators, so myocytes migrate into the intima.

The resulting fatty core is surrounded by connective tissue. The resulting LDL clot cannot be broken down again. This leads to a typical atherosclerotic plaque. The neoplasms contain vessels that arise from the vasa vasorum and cause hemorrhages into the plaque.

Calcium is part of large plaques. Cracks in the endothelium activate coagulation, which is why microthrombosis occurs. Plaques at the initial stage of development do not clog blood vessels. Only when more than 40% of the intima is damaged does stenosis occur. Damage to the vessel wall disrupts NO synthesis, leading to endothelial dysfunction.

Treatment of plaques in blood vessels

Therapy for cholesterol plaques depends on many factors:

  • Stages of the disease;
  • Causes of occurrence;
  • Severity of the disease, etc.

If diagnostic studies reveal non-serious deviations from the norm, then treatment will begin with lifestyle changes and nutritional correction.

Lifestyle changes and diet for atherosclerosis

Changing your lifestyle starts with changing your eating behavior. The doctor must explain to the patient that he is not prescribing a temporary diet on which he must suffer, endure to the end, achieve results, and then return to his previous lifestyle. No. That's not how it works.

First of all, you need to explain to the patient that by replacing foods that are harmful to him with healthy ones, no tragedy occurs. On the contrary, by changing his diet, he moves to a qualitatively better standard of living.

The diet for atherosclerosis recommends eating the following foods:

  • All kinds of seasonal vegetables;
  • Abundance of fruits;
  • Fresh berries;
  • Any types of fish;
  • Lean meats;
  • Vegetable oils;
  • Low-fat fermented milk products.

It is not recommended to consume foods containing large amounts of animal fats. And this:

  1. Fatty meats (especially pork);
  2. Salo;
  3. Bird peel;
  4. Sour cream and other dairy products with a high percentage of fat content.

It is also not recommended to abuse salt, consume foods with flavor enhancers, preservatives, and palm oil.

In addition to diet, it is recommended to make adjustments to your lifestyle. People who lead an active life have a much better metabolism, so you need to move as much as possible and do as much physical exercise as possible.

For the sake of your own health and future happy life, you can and should give up bad habits.

Drug therapy

If nutritional correction is ineffective, the doctor prescribes appropriate therapy. Typically, three types of medications are prescribed for atherosclerosis:

  1. Statins. Drugs in this group block the production of cholesterol by the liver. This is necessary in order to reduce overall cholesterol levels.
  2. A nicotinic acid. Promotes vasodilation, thereby improving blood flow.
  3. Fatty acid sequestrants. They are needed so that the liver uses lipoproteins to more actively digest food.

When prescribing a doctor, you must strictly follow his instructions. You cannot stop taking one or another drug on your own, as some of them require gradual withdrawal.

You should not replace one medicine with another without your doctor’s knowledge, as this may have negative consequences.

Surgical methods of treatment

When there is a threat of a blood clot breaking off, or the disease is advanced and conservative therapy does not help, surgical intervention is possible.

At the moment, there are three most popular and effective operations:

  • Shunting. The essence of this method is that a worn-out vessel is sutured to a healthy one, thereby creating a new bloodstream. Over time, blood flow in the affected area is completely restored, and nutrition to the affected tissue is resumed.
  • Angioplasty. A catheter equipped with a camera is inserted through the femoral artery. By slowly advancing it, the doctor is able to track its entry into the affected area. When the goal is achieved, the doctor carries out all the necessary procedures to cleanse the vessel and expand its lumen. Next, the catheter is also removed from the artery. The cleaned vessel begins to function normally, and the patient’s health is restored.
  • Vascular prosthetics. The essence of this operation is to replace the affected vessels. When the vessel is completely worn out and its cleaning is no longer possible, this method is used. For modern surgery this is not particularly difficult.

Timely consultation with a doctor and prevention of atherosclerosis save many patients from the need for surgical intervention.

Traditional methods of treatment

In consultation with your doctor, you can resort to traditional methods. The following recipes have proven to be best in the treatment of atherosclerotic plaques:

  1. We put the cones and needles of pine needles into a two-liter jar, fill them with vodka and leave for ten days. After the expiration date, you need to add 15 drops of the resulting tincture into water and consume it before meals.
  2. Decoction from plants. To prepare it you need to take: hawthorn or burdock root, or red clover, or sweet clover. You can't mix them. Only one of the listed elements is needed for the decoction. Take a large tablespoon of any of these herbal preparations, add hot water and boil for two minutes. Next, you need to wrap the resulting decoction and let it sit for half an hour. After this, you can consume 70 grams of the decoction before meals.
  3. Herbal compress. Dry herbs are mixed in equal quantities: St. John's wort, string, sage, chamomile and plantain. Take a tablespoon from the resulting mixture, pour a glass of boiling water and leave for half an hour. Next, you need to moisten gauze in it and apply it to the affected areas. This compress is good for atherosclerosis of the lower extremities.

It is important to understand that you cannot rely only on traditional medicine recipes. But in combination with medications, diet and lifestyle changes, they give good results.

Causes

The exact causes of deposits in the arteries are unknown. It is believed that the main thing is a high level of bad cholesterol (LDL) in the blood. In addition, doctors identify a number of factors that contribute to the progression of the disease and more rapid formation of atherosclerotic plaques:

  • smoking;
  • high blood pressure;
  • a large amount of animal fats in food;
  • a small amount of vegetables, herbs, fruits;
  • excess weight and abdominal fat deposition;
  • constant overeating;
  • increased blood glucose levels;
  • physical inactivity;
  • alcohol abuse;
  • natural processes of aging of the body.
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