A VSD student, who once “had the honor” of getting acquainted with the Anaprilin tablet and received tangible relief from it, immediately adds such a friend to his first aid kit. The drug is cheap, always available, and most importantly, Anaprilin really helps with panic attacks.
The heart immediately calms down, the mood becomes better, and the body stops trembling in a panic spasm. Isn't it magic? Pharmacists do not require a prescription, which means that the medicine will not make the patient addicted to drugs and doomed.
Therefore, many VSD sufferers “prescribe” treatment with Anaprilin to themselves: daily and safely at any time of the day to prevent PA. Where does all the hypochondria disappear at such a moment? Anaprilin reliably helps out its “master” during attacks, but it is not as harmless as the VSD specialist wants to believe.
Mechanism of action
After oral administration, the drug is quickly absorbed, as it has pronounced lipophilicity. Penetrates well into all organs and tissues, passes through the blood-brain barrier (acts on the central nervous system).
An effective reduction in heart rate and blood pressure is observed within 20 minutes after administration.
Tablets Anaprilin 40 mg
The half-life ranges from 3 to 6 hours, making it an excellent remedy for emergency use. Metabolized primarily in the liver and excreted by the kidneys. There are a number of interesting indications for the use of the drug, for example, for vascular neoplasms - hemangiomas.
Indications for the use of Anaprilin are determined by the doctor. Do not self-medicate.
In the case of hemangiomas, the mechanism of action has not been precisely established, but scientists claim that propranolol affects the processes of cell division and growth.
The influence of anaprilin on the functioning of the body
If a person really has organic pathologies in which Anaprilin will have a beneficial effect, the doctor will assess all the risks and prescribe a treatment regimen. Anaprilin, acting on adrenaline receptors, at the same time:
- Strongly lowers blood pressure;
- Makes the heart beat slower, softer;
- Reduces the oxygen needs of the heart;
- Lowers blood sugar;
- Makes the gastrointestinal tract work more actively;
- Forces the muscles of the uterus and bronchi to contract strongly;
- Inhibits reactions and thought processes;
With VSD, as a rule, a person rarely suffers from any serious illnesses, plus Anaprilin does not require a prescription - this makes one believe in the complete safety of treatment with this drug. But what happens to the relatively healthy body of a VSD sufferer when taking Anaprilin uncontrolled?
- The pressure is constantly forced to fall down. Sometimes the patient tries to prevent an adrenaline crisis and takes a pill with low blood pressure. The result of such an experiment “for good” can be a sharp decrease in pressure up to fainting, bradycardia, heart failure, pulmonary edema, cardiac arrest. Never take anaprilin with normal and low blood pressure!
- Taking Anaprilin during panic attacks, a person forces his body to experience “perplexity” every time. Any interference with normal functioning (stress, by the way, is also normal from the point of view of nature) forces the body to “think” that it is “broken” and urgently look for methods of “repair”. When the nerve endings are switched off, the body, in order to correct the situation, first increases the production of adrenaline, forcing the adrenergic receptors to finally respond to the hormone. Next, the body increases the number of beta-adrenergic receptors themselves. Now imagine that a person, after long-term use, abruptly discontinues the drug. How acutely he will feel the enormous release of adrenaline with his freshly grown beta-adrenergic receptors! And plus to this - tachycardia, high numbers on the tonometer, this will probably all greatly frighten you.
It becomes clear how dangerous any thoughtless interference in the coordinated work of organs and systems can be. But is it possible to take the drug at all? Answer: yes. But, as with any other medication, caution and vigilance should be exercised.
Anaprilin - dosages depending on the diagnosis
The most common indications for prescribing Anaprilin are arterial hypertension and heart rhythm disturbances. In this case, the starting dose is from 10 to 20 mg 2-4 times a day.
Under blood pressure control, preferably in a cardiology hospital, it can be increased to 40 mg.
The tablet is taken 10 minutes before meals, washed down with a glass of water. This mode is used for long-term stabilization of blood pressure. During a hypertensive crisis, it is recommended to keep 20 mg of Anaprilin under the tongue until completely absorbed. If there is no effect, the dose is repeated after 20 minutes.
There are forms of Anaprilin for intravenous administration of the drug; their use is limited only to specialized departments.
The above doses and modes of administration do not apply to special cases that require medical supervision.
Anaprilin or Concor - which is better for tachycardia
Manufacturer: Takeda Pharmacytilax, Germany
Release form: tablets
Active ingredient: bisoprolol hemifumarate
Concor is an analogue of Anaprilin tablets, which is a selective beta1-blocker, without its own symptomatic activity.
Concor is recommended to be taken for high blood pressure, ischemia, and heart failure, regardless of type. Before starting the course, it is necessary to take into account contraindications and drug interactions. You should not take the analogue during pregnancy and breastfeeding.
As for the reviews, they are positive, since if all recommendations and dosage are followed, a positive effect is observed.
Start of action
When taken orally, the effect develops after 20-30 minutes, the maximum effect is achieved after 2 hours.
Sublingual application (under the tongue) allows you to achieve the desired result within 10-15 minutes.
With long-term use, phenomena of addiction and decreased effectiveness may develop, which are manifested by tolerance to the standard dose and prolongation of the onset of action.
In such cases, consult your doctor to adjust your therapy.
How to take the pills?
The drug has the greatest effect if taken before meals.
It is advisable to eat 15-20 minutes after the medicine is taken, as this will help protect the stomach and intestines from adverse effects.
Speaking about how long it takes for Anaprilin to take effect, we must also talk about the methods of taking it. If it is necessary for the medicine to begin to act as quickly as possible, it is placed under the tongue.
The result will come within 15 minutes, although the tongue may become numb for a short time. When there is no such need, take the tablet with plenty of water. The effect occurs after one and a half to two hours.
Interaction with other drugs
Since Anaprilin has the ability to “relax” the heart muscle and cause spasm of smooth muscles, pharmacological synergism with many drugs can contribute to a number of undesirable effects. Most often, such interactions are manifested by a decrease in blood pressure, severe bradycardia, and disturbances in the electrical activity of the heart.
The list of drugs that can have perverse effects in combination with Anaprilin (most often) is as follows:
- Verapamil (possible development of complete atrioventricular block);
- Adrenalin;
- Salbutamol and Salmeterol;
- Clonidine;
- Isoprenaline;
- Lidocaine;
- Phenobarbital;
- Rifampicin.
It is important to note that when taken concomitantly with insulin or oral hypoglycemic drugs, the symptoms of hypoglycemia may be masked.
The drug is not compatible with alcohol.
Do not forget to inform your doctor about what medications you are taking at the time of starting Anaprilin therapy.
Cost and terms of dispensing from pharmacies
The price of 50 tablets of Anaprilin 10 mg is from 17 rubles.
A prescription is not needed to purchase this drug.
There are contraindications. Specialist consultation required
The medication is sold strictly according to a prescription; you can buy it at the city pharmacy. Before starting the course, be sure to check the expiration date (4 years from the date of release of the tablets). Aaprylin should be stored in a dark place at a temperature of 8-25 degrees, and contact with small children should be completely avoided.
- Store in original packaging at a temperature not exceeding 25 ° C. Keep out of the reach of children.
- Shelf life: 4 years.
Contraindications
Propranolol may be contraindicated in people with the following conditions:
- bronchial asthma;
- chronic obstructive pulmonary disease (COPD);
- bradycardia (less than 60 beats per minute);
- weakness of the sinus node;
- atrioventricular block;
- shocks of various origins;
- severe arterial hypotension;
- cocaine overdose;
- hypersensitivity reactions (urticaria, Quincke's edema, anaphylaxis).
There is evidence that Anaprilin has a negative effect on libido and reproductive ability in men.
Analogs
How to replace Anaprilin? The active substance, propranolol hydrochloride, is contained in a number of medicines as an active substance. We can say with confidence that the following drugs are analogues and are similar not only in composition, but also in effects, contraindications and side effects:
- Obzidan;
- Anaprinol;
- Phenazep;
- Betake TR;
- Stobetin;
- Propranolol;
- Noloten;
- Propranobene;
- Propamin.
If you need to replace Anaprilin, then you should consider the following drugs, which are also a beta blocker, but are based on a different active substance. In addition, these medicines are more modern and safer:
- Atenolol;
- Metoprolol;
- Nebivolol;
- Bisoprolol;
- Betaxolol.
Side effects
Often, undesirable effects while taking Anaprilin cause panic in patients and force the doctor to reconsider the therapy. Most of them are transient and quickly disappear after discontinuation of the drug.
List of the most common side effects:
- digestive system : dyspeptic disorders, dry mouth, abdominal discomfort, heartburn;
- cardiovascular system : orthostatic collapse, bradycardia;
- central nervous system: dizziness, sleep disturbance, headache, fatigue, hallucinations;
- skin: redness, rash, itching.
In rare cases, keratoconjunctivitis, dry mucous membranes, and increased attacks of angina are observed. Propranolol can weaken attention and speed of reactions to external stimuli. These phenomena intensify when taken simultaneously with alcohol and sedatives.
Anaprilin is approved in pediatric practice. Used in complex therapy of congenital heart defects, slows the progression of heart failure. Accepted in a cardiology hospital.
Anaprilin passes through the placenta and can adversely affect the growth and development of the fetus. However, it is an essential remedy for the treatment of a wide range of cardiac pathologies in pregnant women. A prerequisite must be the availability of trained medical personnel and the necessary equipment.
Use in pregnant women and during breastfeeding
The drug is prescribed only when the expected benefit to the woman outweighs the potential risk to the fetus. During the use of Anaprilin, strict monitoring of the fetal condition is required. The drug must be discontinued 3 days before delivery.
Possible negative effects on the fetus: bradycardia, hypoglycemia, intrauterine growth retardation. The drug can also cause fetal death or premature birth.
The active substance is absorbed into breast milk, so nursing women should stop breastfeeding during treatment.
Overdose
Intoxication with Anaprilin can have various manifestations.
Most often, in case of overdose, arterial hypotension and bradycardia are observed.
Possible convulsions, blurred vision, bronchospasm. For emergency assistance in order to neutralize the drug, it is necessary to rinse the stomach and take sorbents.
If we talk about Anaprilin, the lethal dose of the drug for an adult is 10-20 g.
In case of overdose, you must call the emergency hotline.
Use in the elderly
Elderly patients should take the drug with caution. Every few months, blood glucose levels are determined in patients with diabetes and kidney function is monitored in elderly patients.
Also, careful medical supervision requires simultaneous use of Anaprilin with hypoglycemic drugs (to prevent the development of hypoglycemia).
Video on the topic
About the benefits of Anaprilin for hypertension and heart disease in the video:
Propranolol has a wide range of indications; the pharmacological effects of the drug have not yet been sufficiently studied. Experiments are being conducted on the use of the drug in oncological and immunological practice. An interesting study was conducted in 1987 among actors and musicians.
As a result, it was found that from 10 to 16% of representatives of these professions take Anaprilin before going on stage. This is due to the ability of propranolol to suppress the activity of the sympathetic nervous system, eliminate tachycardia, anxiety, and excessive sweating.
The information on the MyMedNews.ru website is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment.
MyMedNews.ru
And we also have
Tagista or Betaserk?
Who is it shown to?
The question of what Anaprilin helps with requires a detailed answer. For example, doctors often prescribe this pharmaceutical product to patients with a history of myocardial infarction. The tablets prevent relapse.
Anaprilin - other indications:
- Disturbed heart rhythm caused by arrhythmia, tachyarrhythmia, as well as paroxysmal and sinus tachycardia;
- Angina;
- Ischemia of the heart muscle;
- Hypertension;
- Migraine;
- Poisoning of the body with medications based on digitalis;
- Thyrotoxicosis (as an addition to the main treatment regimen);
- Pheochromocytoma (as part of a treatment regimen).
In obstetrics, Anaprilin can be prescribed as a medicine that stops uterine postpartum bleeding, as well as postoperative bleeding.
