The questions that arise for people taking Picamilon are usually the same. Is Picamilon compatible with alcohol? What are the reviews of the drug from those who have already taken it? How pronounced is the calming effect of these tablets when taking the drug in courses? What is generally known about the action of Picamilon?
The instructions for the drug say that Picamilon is a drug that improves human mental activity. This is a nootropic drug that dilates blood vessels in the brain and reduces their resistance.
Neurometabolic stimulants (that is, nootropic drugs) normalize metabolic processes occurring in brain tissue and also accelerate blood microcirculation. Improved blood circulation leads to improved oxygen saturation of tissues. Picamilon tablets have an antiplatelet effect, that is, they prevent the spontaneous formation of platelets that clog blood vessels.
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“Picamilon” is a tranquilizer that has a psychostimulating effect and relieves apathy, depression, mental retardation and inertia. After taking the pills, consciousness becomes clearer, sleep is more sound, and memory improves. The effect of this drug is multifaceted. In patients who have completed the entire course of treatment.
The following improvements were observed with Picamilon:
- fears disappear
- Anxiety disappears,
- mental capabilities are significantly improved,
- ability to learn and analyze increases,
- increases mental, physical and mental endurance,
- behavior and general condition are normalized.
Doctors use Picamilon in complex therapy aimed at relieving alcohol withdrawal, treating alcoholism and preventing recurrent binge drinking. The use of this drug in case of alcohol dependence should only be carried out under the supervision of a doctor! Incorrect dosage, as well as individual intolerance to the drug, can lead to death.
Composition and active substance
The main component of the drug is nicotinoyl-gamma-aminobutyric acid. The therapeutic solution for injections is produced in the form of a colorless liquid enclosed in ampoules. You can buy 5% and 10% product at the pharmacy. In the second option, the amount of active substance in the solution is doubled.
Picamilon or Actovegin - which is better?
Manufacturer: NYCOMED GMBH (Austria)
Release form: tablets, injection solution, cream, ointment, gel for external use
Active ingredient: deproteinized hemoderivative of calf blood
Both drugs have different active substances and mechanisms of action, but have equivalent indications and are used for vascular diseases. Actovegin will be the best, as it has broader indications.
The medication provides a therapeutic effect not only for vascular pathology of the central nervous system, but also for diseases of the peripheral nervous system, lesions of the skin and mucous membranes. It is easier to tolerate by patients, gives a quick effect and has an injection form of administration.
Pharmacological properties
The action of the active component is aimed at improving metabolism and blood flow in brain tissue and eliminating the symptoms of brain hypoxia.
Pharmacodynamics
The drug promotes vasodilation and has tranquilizing, psychostimulating, antiplatelet and antioxidant properties.
The use of the medication leads to positive changes in the patient’s condition:
- the process of blood circulation in the brain is normalized;
- metabolic processes are enhanced;
- vascular tone decreases;
- the decomposition of glucose is activated;
- blood sugar levels decrease;
- endurance and ability for mental activity increases;
- memory improves;
- sleep patterns are normalized;
- thrombus aggregation is suppressed;
- the blood circulation process in the retina and optic nerve is activated.
Taking the drug can improve motor and speech functions, relieve anxiety and fear, reduce irritability and reduce the effect of ethanol on the central nervous system.
Pharmacokinetics
The active substance is completely absorbed. Penetrating the blood-brain barrier, it is retained in the tissues for a long time. Bioavailability reaches almost 90%. It is excreted unchanged from the body via the kidneys.
Cortexin
Manufacturer: GEROPHARM LLC (Russia)
Release form: powder for the preparation of a solution for intramuscular administration
Active ingredient: polypeptides of the cerebral cortex of cattle
Cortexin is a nootropic drug and contains a complex of polypeptide fractions that has a direct effect on nerve cells, penetrating their structure. This analogue of Picamilon injections improves and restores impaired cognitive disorders (memory, attention), increases resistance to stress, and stimulates the metabolism of nervous tissue.
Indications and contraindications for use
Doctors often prescribe Picamilon in injections if:
- ischemic stroke of mild and moderate severity;
- cerebrovascular insufficiency;
- vegetative-vascular dystonia;
- neuroinfections;
- psychoses of senile manifestations;
- problems with the retina and dysfunction of the optic nerve;
- urinary disorders.
Picamilon in solution is included in the course of treatment of intoxication caused by drinking alcohol. It is also prescribed for the treatment of alcoholic encephalopathy.
In psychotherapy, the medication is used to eliminate asthenic conditions and neuroses, accompanied by increased anxiety and fear, severe irritability and emotional lability.
Picamilon is used to increase the body's resistance to increased physical and mental stress and restore performance. Taking the medication is indicated after suffering a traumatic brain injury.
Although the medicine is well tolerated by patients, experts do not recommend using it for prophylactic purposes, since it affects metabolic processes in the brain.
When treating with the drug, it should be taken into account that there are some restrictions for its use, including:
- hypersensitivity to the active substance;
- severe kidney dysfunction;
- severe liver pathology.
Use in childhood
In pediatrics, Picamilon is often used in urological practice. It is included in the complex therapy of urinary disorders in children. The product has a positive effect on the functioning of the bladder, improving the condition of the organ and reducing the severity of urination disorders.
The use of Picamilon increases the child's cognitive functions, improving his memory, speech and attentiveness. The drug is used for delayed mental, physical and intellectual development in children.
Picamilon increases mental and physical performance in schoolchildren during intense learning loads.
During pregnancy and breastfeeding
The medicine is contraindicated for use during pregnancy and lactation.
Picamilon or Piracetam - which is better?
Manufacturer: JSC SINTEZ (Russia)
Release form: tablets, capsules, injection solution
Active ingredient: piracetam
Piracetam and Picamilon are nootropic drugs that improve cognitive impairment due to hypoxia or intoxication. The Piracetam analogue will be the best for vascular lesions of various origins.
A special feature of Piracetam is its ability to penetrate and concentrate in the area of ischemia. The drug stimulates local metabolism, microcirculation and reduces blood viscosity. For children, Picamilon will be the best, since the medication is safer, increases the child’s mental abilities and has fewer side effects.
Regimen and dosage regimen
When prescribing Picamilon in injections, the instructions for use must be carefully studied in order to obtain the maximum therapeutic effect and not harm the body.
For adults, the drug is administered intramuscularly and intravenously. The recommended method of use depends on the type of pathology, the patient’s condition, his age and the individual characteristics of the body.
If a cerebrovascular accident is diagnosed in an acute or chronic form, 2 ml of 5% or 10% of the drug is administered intravenously in the morning, and in the evening the same dose is injected intramuscularly. The course of therapy can last up to 1 month.
To eliminate a neurosis-like or asthenic condition, injections with a 10% solution (2-4 ml) are used. The medication is administered intramuscularly once a day. The duration of treatment depends on the severity of the symptoms of the disease and is determined individually by the attending physician.
For alcohol withdrawal, intramuscular use (100-300 mg) is indicated. Therapy is carried out for 7 days. If chronic alcoholism is being treated (in the absence of withdrawal symptoms), the dosage is reduced by 2 times and the medication is used for 3-5 days.
To eliminate the symptoms of alcohol poisoning, the drug is first administered intravenously. The saturating dosage is determined at the rate of 5 mg per 1 kg of body weight. Then they switch to the drip method of administration, using 1.56 mg ha per 1 kg of weight for 1 hour.
The use of Picamilon injections as part of complex therapy for cerebrovascular pathologies involves the use of a daily dose of 60-150 mg, divided into 3 doses.
For the treatment of severe depression, the medicine is prescribed both intravenously and intramuscularly. A single dosage is 40-200 mg of 5% product. Injections are given 2-3 times a day. The average course of therapy is 1-2 months.
In case of urination disorder in children, preference is given to the tablet form of the drug. If there is a need to use injections, the dosage is determined individually by the attending physician.
Glycine
Manufacturer: BIOTIKI LLC (Russia)
Release form: tablets
Active ingredient: glycine
Glycine belongs to the group of neurotropic drugs and is a metabolic regulator. The medication reduces the manifestations of neurological symptoms during a stroke, reduces psycho-emotional stress, and normalizes sleep.
The drug is effectively used in pediatric practice to stimulate the mental development of children and improve the learning ability of schoolchildren.
Overdose and possible side effects
There is no information about cases of overdose. If recommended doses are exceeded, negative reactions from the body may occur, including:
- allergies accompanied by itching, skin rash, redness and swelling;
- headache and dizziness;
- increased anxiety and irritability;
- the appearance of a feeling of fear;
- rushes of blood to the face and head.
If side effects are observed, it is recommended to consult with your doctor, who can adjust the dosage or replace the drug with a similar drug.
Cytoflavin
Manufacturer: POLYSAN LLC (Russia)
Release form: tablets, injection solution
Active ingredient: inosine, nicotinamide, riboflavin, succinic acid
Cytoflavin is a combination drug that has a metabolic effect with a high degree of bioavailability.
The medication improves the function of interstitial respiration and metabolism in the cells of the central nervous system, stimulates protein biosynthesis and eliminates cognitive disorders.
What else can replace Picamilon, what effective drugs that improve the functions of the central nervous system?
You can supplement the list of medications by the following means:
- A nicotinic acid:
- Nootropil;
- Encephabol:
- Pentoxifylline;
- Cerebrolysin;
- Noopept;
- Ceregamon;
- Afobazole;
- Anvifen;
- Vasobral;
- Mildronate;
- Betahistine;
- Cereton;
- Ceraxon;
- Ginko biloba;
- Lutsetam;
- Sermion;
- Noben;
- Gammalon;
- Phezam.
Among these substitutes there are analogues of Picamilon for children, which are widely used in pediatric practice.
A properly selected analogue of Picamilon 50 mg will make it possible to stimulate cerebral blood flow in cerebral insufficiency of various origins, improve the functions of the central nervous system and prevent further development of the disease.
Active analogues
If necessary, Picamilon can be replaced with drugs similar in composition and therapeutic effect. The most commonly used of them:
- Cavinton. It has a positive effect on brain metabolism, ensuring an increase in the consumption of glucose and oxygen by the cells of the organ. Helps increase the resistance of neurons to hypoxia, reduce platelet aggregation and blood viscosity. Widely used in neurology and ophthalmology. Intended for intravenous and intramuscular administration without prior dilution.
- Piracetam. A derivative of gamma-aminobutyric acid improves metabolic processes and normalizes cerebral circulation. Provides stimulation of redox reactions in tissues and promotes glucose utilization. As the patient's condition improves, the dosage of the drug is gradually reduced, and a transition to the tablet form of the drug is made.
- Cellex. Has neuroprotective properties. The drug contains polypeptides from the brain of pigs as an active ingredient. It is used as part of complex therapy for acute and chronic disorders of cerebral blood flow and during the rehabilitation period to reduce the recovery time of a patient with a disorder of the central and peripheral nervous system of vascular origin.
- Amylonosar. The nootropic drug is intended for the correction of cerebrovascular accidents; contains nicotinoyl-gamma-aminobutyric acid. It has psychostimulating, antiplatelet, antioxidant and anxiolytic properties; helps to increase the volume of cerebral blood flow and reduce vascular resistance. It is used in neurology to reduce headache attacks, normalize sleep, eliminate motor and speech disorders, and also to increase physical and mental performance.
- Vinpocetine. The active substance has psychostimulating and nootropic properties. It has a positive effect on metabolic processes in the brain, improving its blood supply and rheological properties of blood. Under the influence of the active component, an increase in the uptake of glucose and oxygen and their consumption by brain tissue is stimulated. The drug helps reduce blood viscosity and vascular resistance in the organ.
- Cerebrolysin. A representative of psychostimulants and nootropics contains a proteolytic peptide fraction obtained from pig brain. When used, it improves the condition of brain cells and activates the mechanism of their protection and restoration. Stabilizes blood microcirculation and normalizes cognitive functions.
Only the attending physician should select an analogue and make changes to the treatment regimen, taking into account the individual characteristics of the body, the course of the disease, chronic diseases and the age of the patient.
Picamilon or Phenibut - which is better and more effective, what is the difference
Manufacturer: JSC ORGANIKA (Russia)
Release form: tablets
Active ingredient: aminophenylbutyric acid
Phenibut and Picamilon have a nootropic effect and are in the same pharmacological group, but act on the body through different mechanisms. The difference between the drugs is:
- The release form is Picamilon in tablets and ampoules, and its analog Phenibut is only in tablets.
- Composition of main and auxiliary ingredients.
- Vasodilator effect - Picamilon dilates blood vessels, but Phenibut does not.
- Possibility of developing addiction - long-term therapy with Phenibut can provoke addiction.
- The advantage of the effect is that Phenibut is more effective as a tranquilizer, and Picamilon as a nootropic.
According to patient reviews, Phenibut copes well with asthenia, insomnia, anxiety, unmotivated fear and will be the best for psychosomatic diseases accompanied by these symptoms.
Answers on questions
Is Picamilon an antidepressant or not?
No, the medication is a nootropic that acts on the vascular system.
Does Picamilon Increase or Lower Blood Pressure?
The drug has a vasodilating effect, which leads to a decrease in blood pressure.
Should Picamilon be dissolved or swallowed?
Picamilon tablets should be swallowed and washed down with plenty of water.
Does Picamilon thin the blood or not?
Yes, the medication thins the blood and prevents the formation of blood clots.
Does Picamilon have a cumulative effect or does it work immediately?
The drug acts immediately and does not have a cumulative effect.
Are Picamilon injections painful or not?
IM injections of Picamilon cause minor pain.
